stephany Par Le 20/05/2020 à 13:20 comment 0

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With early detection of prostate cancer, the chances of a full recovery are very high!




The prostate is a gland that forms a fluid that forms part of sperm. The prostate lies just below the bladder in front of the rectum. It surrounds the urethra (which carries urine and semen through the penis from the body).

 The urethra passes through the prostate gland. The prostate is supplied with blood by numerous small arterial branches, venous blood flows from it into the venous plexus of the prostate. Lymph from the prostate gland flows into the lymph nodes of the pelvis. Lymph nodes are part of the lymphatic system, which fights infection and disease, and serve as original filters in which foreign agents settle.


Prostate cancer usually grows very slowly. Most men with prostate cancer are over 65 and do not die from this disease. Finding and treating prostate cancer before symptoms appear can improve your health or help you live longer. Talk with your doctor about your risk of developing prostate cancer and whether you need screening tests.


Understanding Prostate Changes - National Cancer Institute


The prostate is an organ of the male reproductive system. It is located under the bladder. The urethra passes through the prostate. A healthy prostate has a spherical shape and resembles a chestnut fruit. Its value depends on age. The prostate is involved in the production of seminal fluid. During ejaculation with the help of seminal fluid, semen is released. If the prostate is greatly enlarged, then it narrows the lumen of the urethra. This can hinder or stop the flow of urine from the bladder to the urethra.




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  1. Fighting cancer cells.
  2. To prevent cancer cells from spreading to other organs.
  3. To strengthen the body's defense against other diseases by strengthening the immune system.
  4. To increase the effect of chemotherapy and radiotherapy.
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What are the prostate tumors?

The most common diseases of the prostate gland are prostatitis (inflammation of the prostate gland) and benign prostatic hyperplasia (BPH).

BPH is not a tumor, but is an excessive formation of normal prostate cells, when the gland enlarges, squeezes the urethra and blocks the normal flow of urine. You should know that BPH cannot degenerate into a malignant tumor and develops from other cells than prostate cancer !!!

However, the presence of prostatitis or BPH does not exclude the possibility of a man having prostate cancer.

BPH is a common disease, the frequency of which increases with age.





5 Prostate cancer facts a Ghanaian Man should know | Viva Health ...

Prostate cancer is a malignant tumor. Cancer develops in the peripheral parts of the prostate gland, so the clinical manifestations of the tumor appear in the late stages of the disease. As the size of the neoplasm increases, compression of the urethra occurs, which leads to difficulty in urinating and urinary retention. Germination of a tumor in the bladder and rectum can lead to bleeding. In addition, a prostate tumor can spread throughout the body with the appearance of metastases in the lymph nodes, bones, lungs, and liver.


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Prostate cancer is most common in men above 50.


That is why men over 50 years of age are recommended to undergo an annual examination for prostate cancer, especially if there are the following symptoms:

  • Weight loss
  • Difficulty urinating
  • Frequent and painful urination
  • Perineal pain
  • Pelvic pain
  • Back pain 
  • Scrotum pain
  • Blood in urine, blood in semen, etc.



Who is more likely to develop prostate cancer?

Black Men Less Likely to Get Proper Prostate Cancer Treatment | CTCA

It is far from always possible to answer the question - why does one person get prostate cancer and another does not, however, it is known that in people with certain risk factors, PCa is more common.


Studies have identified the following risk factors for prostate cancer:

  1. age over 65 years. Age is a major risk factor for prostate cancer. Most patients with prostate cancer are over 65 years old. This disease is rare in men under the age of 45;
  2. heredity. If one of the next of kin (father, brother) has prostate cancer, then the risk of the disease doubles. If prostate cancer is detected in two relatives, then the risk increases by more than 5 times;
  3. ethnicity. It has been proven that prostate cancer is more common among members of the Negroid race;
  4. some morphological changes in the prostate gland. These changes at the cellular level are detected only with a biopsy of the prostate gland): in men with prostatic intraepithelial neoplasia (IDU), the risk of developing cancer may be increased;
  5. genetic predisposition. Certain DNA fragments with genes have been identified in which abnormalities increase the risk of developing prostate cancer. If a person has genetic changes in one or more of these areas, then the likelihood of developing PCa increases. In addition, other studies have shown an increased risk of cancer in men with changes in specific genes such as BRCA1 and BRCA2.



How common is prostate cancer?

Prostate cancer is a very common disease. In the world, prostate cancer is the second leading cause of cancer mortality in men. In the Republic of Belarus, the incidence rate of prostate cancer is in 3rd place after skin and lung cancer, and is 46.3 cases per 100 thousand men.



How does prostate cancer manifest?

Prostate cancer may not manifest itself for a long time. Usually the symptoms (signs of the disease) begin to appear with the growth and increase in the size of the tumor.

The most common symptoms of prostate cancer include:

  1. violation of urination;
  2. difficulty urinating (at first it is difficult to start urinating or stop the flow of urine, later on the entire act of urination proceeds with great effort);
  3. pain or burning when urinating;
  4. frequent urination, especially at night;
  5. weak urine flow;
  6. violation of erection;
  7. an admixture of blood in urine or semen;
  8. frequent pain in the lower back, in the pelvis or thigh.




Prostate Cancer Treatment (PDQ®)–Patient Version - National Cancer ...

If the doctor suspects that you may have a prostate tumor, he should refer you to a specialized hospital. An oncourologist will conduct an examination, which will include palpation of the abdomen and all groups of lymph nodes. You will have blood taken from a vein for clinical and biochemical analyzes, urine for a general analysis, electrocardiography (ECG) has been performed. If necessary, your doctor will prescribe other types of examinations.

The main methods for diagnosing prostate cancer are digital rectal examination, determination of the level of prostatic specific antigen (PSA) of blood serum and transrectal ultrasound examination (TRUS).



Digital rectal examination is performed by a specialist - a urologist. During this study, the prostate is probed through the wall of the rectum with a finger inserted into the anus.


PSA is a highly specific tumor marker for prostate cancer. The average concentration of PSA in the blood serum of men who do not suffer from diseases of the prostate gland is 4 ng / ml. PSA levels are age dependent. An increase in PSA levels, in addition to prostate cancer, may be due to prostatitis, benign hyperplasia, transurethral and transrectal manipulations.


TRUSES is a safe research method. A special ultrasound probe is inserted through the anus into the rectum, which allows you to get a clear image of the prostate gland, to detect the presence of a tumor in it, to determine its size, location and degree of prevalence. TRUS does not accurately distinguish between benign and malignant tumors.


To establish an accurate diagnosis, confirmation of the malignant nature of the tumor is necessary, according to microscopic examination of the tumor tissue. In order to obtain pieces of the tumor, a puncture biopsy of the prostate is performed under the control of TRUS. To do this, a special ultrasound probe is inserted through the anus into the rectum, which makes it possible to take prostate tissue from the required area for analysis with a special needle. To obtain the required amount of prostate tissue, 6-12 injections are usually performed.


Ultrasound is a safe and painless examination method. In order for the doctor to be able to better see the pelvic organs, the study is performed with a full bladder. Ultrasound makes it possible to diagnose prostate cancer metastases in the lymph nodes of the pelvis and retroperitoneal space, liver, etc.


Computed tomography (CT) is a special type of X-ray examination that allows you to get an image of the transverse sections of the body. CT makes it possible to determine the condition of the lymph nodes of the pelvis.


Magnetic resonance imaging (MRI) is a special research method that allows you to obtain images of transverse and longitudinal sections of the body. MRI also makes it possible to determine the condition of the pelvic lymph nodes.


Chest x-rays are performed to determine the presence or absence of lung metastases.


This type of examination allows you to determine the presence of metastases in the bones of the skeleton and is prescribed only to patients who have bone pain or an increase in a certain enzyme (alkaline phosphatase) in the blood.


X-ray of the bones of the skeleton is performed in the presence of changes identified during scanning to confirm the presence of metastases in the bone.


Skeleton bone MRI is performed if there are changes identified by scanning to confirm the presence of bone metastases.

After the examination, the stage of the disease is established. Depending on the stage, a decision is made on treatment tactics.




Prostate cancer: The two drugs that can radically delay the spread ...

Treatment methods


Patients with prostate cancer have a large selection of treatments. Treatment can be surgical, radiation, hormonal and combined. If the patient's condition worsens, in this case, treatment is temporarily discontinued.

Treatment may be local (local or systemic).


Local therapy

Surgical or radiation therapy is aimed at removing or destroying cancer in the prostate. When prostate cancer spreads to other parts of the body, local therapy is done to control the disease in specific areas.

Systemic therapy

It is known that hormones affect the course of the tumor process. The correct choice of treatment depends on the stage of the tumor, symptoms, and general health. During treatment, healthy cells and tissues are damaged, various side effects are observed, depending on the type of treatment used.



Surgical Overtreatment of Prostate Cancer May Be Decreasing ...

Surgical treatment is carried out in the early stages of prostate cancer. Each type of surgical treatment has a positive side:

  • Radical posterior prostatectomy.
    • the entire prostate and neighboring lymph nodes are removed through an abdominal incision.
  • Radical perineal prostatectomy.
    • the entire prostate is removed through an incision between the rectum and scrotum. Regional    lymph nodes can be removed through a separate abdominal incision.
  • Laparoscopic prostatectomy.
    • the entire prostate and neighboring lymph nodes are removed through small incisions using a thin light tube (laparoscope).
  • Transurethral resection of the prostate.
    • Part of the prostate is removed using a long thin device inserted into the urethra. Cancer is cut off from the prostate. This operation allows you to remove the part that blocks the outflow of urine.

The healing time after surgical treatment is different for everyone and depends on the type of surgical treatment. After surgery, the urethra needs time to heal. You will have a catheter. A catheter is a tube passing through the urethra into the bladder to drain urine. The catheter will be from five days to three weeks. After surgery, some lose control of urine outflow (urinary incontinence). In many, urinary incontinence recovers in a few weeks. Some men may become impotent. Preservation of the nerve is an attempt to avoid the problem of impotence. Sometimes partial impotence occurs. Removing the prostate leads to infertility. You will have dry orgasms.


Radiation therapy (radiotherapy) is a method of treatment using ionizing radiation. High-energy rays destroy cancer cells only in the affected area. Radiotherapy can also be used after surgery to destroy the remaining cancer cells. In the advanced stages of prostate cancer, radiotherapy is prescribed to relieve pain.

  • Outdoor radiation . Radiation comes through a large installation outside the body. Treatment usually takes 5 days a week for several weeks. Many receive 3-dimensional conformal radiation therapy.
  • Internal radiation (implanted radiation or brachytherapy): Radiation comes from radioactive material in a small seed. The seeds are introduced into tissues that give radiation within a month.

Side effects depend mainly on the dose and type of radiation. You may be very tired during radiation therapy, especially a few weeks after therapy. Rest is needed, but doctors advise patients to try to stay as active as possible.

If you have external radiation, you may have diarrhea or frequent urination with discomfort. Some people have constipation or trouble urinating. Your skin in the treatment area may turn red, become dry and sagging. In the treatment area, hair that does not grow back can fall out.

Internal radiation therapy can cause urinary incontinence. This side effect usually goes away.

Both types of radiation therapy cause impotence. With internal radiation, this effect is less pronounced.


  • Agonists of luteinizing releasing hormone ( LH- RH) , these drugs inhibit testosterone production by the testes.
  • Antiandrogens: These drugs block the action of male hormones. For example flutamide, bicalutamide, nilutamide.
  • Other drugs. Drugs that block the production of testosterone by the adrenal glands. For example, ketoconazole, aminoglutethimide.     

Hormone therapy affects the quality of your life. Side effects such as impotence, hot flashes, lack of sex drive, and bone weakness are often caused. LH-RH agonists can worsen your symptoms for a short time, at the beginning of the dose. This temporary problem is called a “flash." Treatment will gradually lower your testosterone. Without testosterone, the tumor grows slowly.


With the development of side effects, you may be offered active observation. This is due to your age or related illnesses. Observation is suggested in the early stages of cancer if it grows slowly. You will be offered treatment if symptoms appear or the condition worsens.

Observation is performed to avoid or delay side effects associated with surgery and radiation, but this choice is associated with risk. This will decrease the chances of controlling the cancer before it spreads.

Nutrition and physical activity


Men with prostate cancer are very important to take care of themselves. You need to eat well and stay active. You should get enough calories and protein. You must be active. Walking, yoga, swimming support your body. Exercise reduces pain, facilitates treatment, and helps relieve stress. 


Chemotherapy for prostate cancer

Prostate cancer treatment - chemotherapy - Prostate Matters

Chemotherapy refers to the use of drugs that kill cancer cells. Chemotherapy for prostate cancer is used in the case of advanced cancer and when hormone therapy is ineffective. Chemotherapy is usually done in cycles.

Each cycle has a treatment period and a rest period. Side effects depend on the chemotherapy and its individual tolerance. To reduce damage to healthy tissues, the dose and frequency of chemotherapy are monitored.


Prostate Cancer Prevention

Prostate Cancer Prevention with Proper Nutrition

What is prevention?

Cancer Prevention is an action to reduce the chance of getting cancer. By preventing cancer, the number of new cases of cancer in a group or population is reduced.

To prevent the launch of new cancers, scientists are considering risk factors and protective factors. Anything that increases your chances of developing cancer is called a cancer risk factor; anything that reduces your chances of developing cancer is called a protective factor for cancer.

Some risk factors for cancer can be avoided, but many cannot. For example, both smoking and the inheritance of certain genes are risk factors for some types of cancer, but only smoking can be avoided. Regular exercise and a healthy diet can be protective factors for some cancers. Avoiding risk factors and increasing protective factors can reduce your risk, but this does not mean that you will not have cancer.

Researchers are exploring ways to prevent prostate cancer.

  • Diet. The antioxidants leukopins found in tomatoes and some fruits and vegetables help prevent prostate cancer.
  • Supplements to the diet. We are studying the reduction of cancer risk under the influence of selenium and vitamin E.
  • Preparations . Research is being done on the prevention of prostate cancer. The effects of finasteride are being studied. The drug reduces the development of prostate cancer. Although men who developed prostate cancer while taking the drug had a more malignant form of cancer, you should notify your doctor about taking this drug.



Screening promotes early detection and treatment of cancer. Screening and early diagnosis of prostate cancer allow doctors to conduct timely, radical and optimal treatment. Delivering patients from palliative non-radical treatment and numerous hospitalizations.


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